Bontril is a medicine that is used to reduce weight . There is a great need to exercise caution when phendimetrazine tartrate is prescribed even under mild conditions such as mild hypertension. There is a chance that the hypotensive effect of guanethidine is decreased due to phendimetrazine tartrate.
Alteration in insulin requirements among patients with diabetes mellitus may occur when it is used in association with phendimetrazine tartrate and hence the associated dietary process is also altered.
It is necessary to prescribe the least amount of the drug at one time so that the chances of over dosage become minimized. There is no evidence of the safe use of this drug during pregnancy. It is advised that phendimetrazine tartrate is not given to women who are pregnant or are planning to become pregnant unless more information is available about the use of this drug for pregnant women.
There may be a chance of using the drug by pregnant women only in the case when the possible hazards are outweighed by the potential benefits of the drug.
It is highly advised not to prescribe this drug to the children that are younger than 12 years of age.
Some adverse reactions may occur due to the use of this drug such as cardiovascular problems such as tachycardia, palpitation and increased blood pressure; central nervous system problems such as restlessness, insomnia, headache, agitation, sweating, over stimulation, dizziness, tremor, rarely psychotic episodes at recommended doses, flushing and blurring of vision; gastrointestinal problems such as diarrhea, nausea, dryness of the mouth, constipation and stomach pain; genitourinary problems such as urinary frequency, changes in libido and dysuria.
Effects on cardiovascular systems may also occur such as hypertension, circulatory collapse, arrhythmia's, and hypo tension. Problems have also occurred in the gastrointestinal system due to the over dosage of the drug such as vomiting, diarrhea, nausea and abdominal cramps. It is also found that poisoning due to the over dosage of the drug has resulted in coma, convulsions and death.
The excretion of Phendimetrazine tartrate is increased due to the acidification of the urine.
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