Bontril (Phendimetrazine tartrate) has the chemical name of (+)-3,4-Dimethyl-2-phenylmorpholine Tartrate.
Phendimetrazine tartrate is white in color with any odor, with bitter taste in the form of powder. It is soluble in methanol, water and ethanol.
Phendimetrazine tartrate has the pharmacological activity that is the same as the activity of the prototype drugs of the same class that are used in obesity.
They are called amphetamines. Phendimetrazine tartrate is used to stimulate central nervous system and to elevate the blood pressure. All the drugs of this class are found to have tolerance and tachyphylaxis that is commonly found in all the drugs that are used for the same purpose.
Phendimetrazine tartrate and other drugs of this class are commonly called anorectics or anorexigenics. Still, the function of Phendimetrazine tartrate is not established as to decrease the body weight and to suppress appetite.
compared to the magnitude of weight loss among placebo treated patients but this difference is only a fraction of a pound a week.
It is also found that the weight decreases quickly in the first weeks among the patients that are treated over both the drug and placebo. Then the rate of weight decrease drops in the following weeks.
Variations are found in the weight loss due to Phendimetrazine tartrate from trial to trial and it is suggested that the significant decrease in the weight in the first weeks is probably due to variables rather than the drug.
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